Shelf Life Of Warfarin

Warfarin tablets 5 mg are pink flat round tablets plain on one side and scored on the other with w and 5 on either side of the line.

Shelf life of warfarin.

The clearance of r warfarin is generally half that of s warfarin thus as the volumes of distribution are similar the half life of r warfarin is longer than that of s warfarin. Do not store above 25 c. Store in the original. Single dosages should not exceed 5000 iu 200 ml.

It is commonly used to treat blood clots such as deep vein thrombosis and pulmonary embolism and to prevent stroke in people who have atrial fibrillation valvular heart disease or artificial heart valves. However the effective half life ranges from 20 to 60 hours with a mean of about 40 hours. Marketing authorisation holder and manufacturer. The half life of r warfarin ranges from 37 to 89 hours while that of s warfarin ranges from 21 to 43 hours.

The best evidence that some drugs can last past their expiration date is from the shelf life extension program slep undertaken by the fda for the department of defense. Warfarin sold under the brand name coumadin among others is a medication that is used as an anticoagulant blood thinner. The wisdom suggests that if your life does depend on an outdated drug and you must have 100 of the original strength it is wise to follow the cliché better safe than sorry. The shelf life of many drugs it wrote seems to be considerably longer than their expiration dates leading to unnecessary waste higher pharmaceutical costs and possibly reduced access to.

Dosage for inr 3 5. The terminal half life of warfarin after a single dose is approximately 1 week. It has a centuries long history of being used to treat medical ailments primarily. Packs contain 21 28 50 100 200 or 500 tablets.

Bromelain is a protein digesting enzyme mixture derived from the stem fruit and juice of the pineapple plant. Not all pack sizes may be marketed. Dosage for inr 6 0. Studies with radiolabeled drug have demonstrated that up to 92 of the orally administered dose is recovered in urine.

If your life does not depend on an expired drug such as you have headache common cold or constipation you may take the medication and see what happens. The original purpose of the slep program was twofold. To determine the actual shelf life of stockpiled military medications for future use and to save government. Risk exists for thromboembolic episodes.